β-Lactamase-Producing, Ciprofloxacin-Resistant Neisseria meningitidis Isolated From a 5-Month-Old Boy in the United States

J Pediatric Infect Dis Soc. 2021 Apr 3;10(3):379-381. doi: 10.1093/jpids/piaa085.

Abstract

Worldwide, there have been few reports of β-lactamases causing penicillin resistance in Neisseria meningitidis. The first known case of disease in the United States due to a β-lactamase-producing, ciprofloxacin-resistant N. meningitidis was recently identified. This has potential implications on standard laboratory testing and empiric management of meningococcal disease.

Keywords: Neisseria meningitidis; antibacterial agents; antibiotic prophylaxis; drug resistance; microbial; β-lactamases.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Ciprofloxacin / therapeutic use
  • Humans
  • Infant
  • Male
  • Meningococcal Infections* / diagnosis
  • Meningococcal Infections* / drug therapy
  • Microbial Sensitivity Tests
  • Neisseria meningitidis*
  • United States

Substances

  • Anti-Bacterial Agents
  • Ciprofloxacin