Two cases of spindle cell variant diffuse large B-cell lymphoma of the uterine cervix

Hiroko Murata; Harumi Nakamura; Yukinobu Ohta; Masanori Kitamura; Shinichi Nakastuka; Jun Ishikawa; Shoji Kamiura

doi:10.1016/j.gore.2020.100611

Two cases of spindle cell variant diffuse large B-cell lymphoma of the uterine cervix

Gynecol Oncol Rep. 2020 Jul 15:33:100611. doi: 10.1016/j.gore.2020.100611. eCollection 2020 Aug.

Authors

Hiroko Murata¹, Harumi Nakamura², Yukinobu Ohta¹, Masanori Kitamura², Shinichi Nakastuka², Jun Ishikawa³, Shoji Kamiura¹

Affiliations

¹ Department of Gynecologic Oncology, Osaka International Cancer Institute, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka 841-8567, Japan.
² Department of Pathology, Osaka International Cancer Institute, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka 841-8567, Japan.
³ Department of Hematology, Osaka International Cancer Institute, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka 841-8567, Japan.

Abstract

Lymphoma with prominent spindle cell features is a morphological variant of diffuse large B-cell lymphoma (DLBCL) and is categorized as a rare variant by the WHO classification. Most cases arise from the skin, with only two cases reported in the uterine cervix to date. Here, we report two cases of spindle cell variant DLBCL of the uterine cervix. Although these cases might be rare, we believe that, as gynecologists and pathologists increase their knowledge of this variant type, more cases will be diagnosed properly.

Keywords: Malignant lymphoma; Needle biopsy; R-CHOP chemotherapy; Spindle cell variant DLBCL; Uterine cervix.

Publication types

Case Reports