The recent version of pediatric septic shock guidelines, 2020 have addressed practical issues pertaining to pediatric septic shock management, which can be applicable to resource-limited setting as well. Supportive aspects in management of septic shock such as ventilation, antibiotic stewardship, and nutrition are addressed compared to previous guidelines that concentrated more on first-hour management. The current guideline needs to be adapted to local clinical practice cautiously in the light of experience, clinical acumen and judgement.