Guillain-Barre Syndrome After Craniocerebral Gunshot Injury: First Report

World Neurosurg. 2020 Nov:143:23-25. doi: 10.1016/j.wneu.2020.07.103. Epub 2020 Jul 22.

Abstract

Background: Guillain-Barre syndrome (GBS) is a rare but serious disorder involving peripheral nerve inflammatory demyelination characterized by acute onset tetraparesis and areflexia. Generally, GBS is preceded by a bacterial or viral infection, and post-traumatic or postsurgical GBS is rarely seen.

Case description: A 41-year-old man with severe craniocerebral gunshot injury and open depressed occipital bone fracture was operated urgently. Two weeks postoperatively, he suffered from sudden quadriparesis. He had flaccid paralysis of his bilateral muscle lower extremities (0/5), along with bilateral upper extremity weakness (2/5).

Conclusions: We report the first case, to our knowledge, with post-traumatic GBS after craniocerebral gunshot injury. We want to indicate the possibility of post-traumatic GBS in cases of unexplained quadriparesis or quadriplegia after trauma or surgery.

Keywords: Guillain-Barre syndrome; Gunshot; Head injury.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Contusion / diagnostic imaging
  • Electrodiagnosis
  • Fractures, Open / diagnostic imaging
  • Fractures, Open / surgery*
  • Guillain-Barre Syndrome / diagnosis*
  • Guillain-Barre Syndrome / physiopathology
  • Guillain-Barre Syndrome / therapy
  • Head Injuries, Penetrating / diagnostic imaging
  • Head Injuries, Penetrating / surgery*
  • Hematoma, Subdural, Intracranial / diagnostic imaging
  • Hematoma, Subdural, Intracranial / surgery
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Immunologic Factors / therapeutic use
  • Male
  • Neural Conduction
  • Neurosurgical Procedures
  • Occipital Bone / diagnostic imaging
  • Occipital Bone / injuries
  • Occipital Bone / surgery
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / physiopathology
  • Postoperative Complications / therapy
  • Quadriplegia / physiopathology*
  • Quadriplegia / therapy
  • Respiratory Insufficiency / physiopathology*
  • Respiratory Insufficiency / therapy
  • Skull Fractures / diagnostic imaging
  • Skull Fractures / surgery*
  • Wounds, Gunshot / diagnostic imaging
  • Wounds, Gunshot / surgery*

Substances

  • Immunoglobulins, Intravenous
  • Immunologic Factors