Genotypic Heterogeneity of Orientia tsutsugamushi in Scrub Typhus Patients and Thrombocytopenia Syndrome Co-infection, Myanmar

Emerg Infect Dis. 2020 Aug;26(8):1878-1881. doi: 10.3201/eid2608.200135.

Abstract

Serologic and molecular surveillance of serum collected from 152 suspected scrub typhus patients in Myanmar revealed Orientia tsutsugamushi of genotypic heterogeneity. In addition, potential co-infection with severe fever with thrombocytopenia syndrome virus was observed in 5 (3.3%) patients. Both scrub typhus and severe fever with thrombocytopenia syndrome are endemic in Myanmar.

Keywords: Bacteria; Myanmar; Orientia tsutsugamushi; co-infection; differential diagnosis genotypes; mite-borne infections; phylogenic analysis; scrub typhus; thrombocytopenia syndrome virus; tsutsugamushi; vector-borne infections; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Coinfection* / epidemiology
  • Humans
  • Myanmar / epidemiology
  • Orientia
  • Orientia tsutsugamushi* / genetics
  • Scrub Typhus* / complications
  • Scrub Typhus* / diagnosis
  • Scrub Typhus* / epidemiology
  • Thrombocytopenia*