High-Intensity Interval Training Decreases Muscle Sympathetic Nerve Activity and Improves Peripheral Vascular Function in Patients With Heart Failure With Reduced Ejection Fraction

Circ Heart Fail. 2020 Aug;13(8):e007121. doi: 10.1161/CIRCHEARTFAILURE.120.007121. Epub 2020 Jul 16.

Allan R K Sales^{1

2}, Luciene F Azevedo¹, Thiago O C Silva¹, Amanda G Rodrigues¹, Patricia A Oliveira¹, Camila P Jordão¹, Ana C M Andrade¹, Ursula Urias^{1

3}, Guilherme V Guimaraes¹, Edimar A Bocchi¹, Maria Janieire N N Alves¹, Ludhmila A Hajjar¹, Roberto K Filho¹, Zachary I Grunewald^{4

5}, Luis A Martinez-Lemus^{5

3}, Jaume Padilla^{4

5}, Carlos E Negrão^{1

6}

¹ Heart Institute (InCor), University of São Paulo Medical School, Brazil (A.R.K.S., L.F.A., T.O.C.S., A.G.R., P.A.O., C.P.J., A.C.M.A., U.U., G.V.G., E.A.B., M.J.N.N.A., L.A.H., R.K.F., C.E.N.).
² D'Or Institute for Research and Education (IDOR), São Paulo, Brazil (A.R.K.S.).
³ Department of Medical Pharmacology Physiology (U.U., L.A.M.-.L.), University of Missouri, Columbia.
⁴ Department of Nutrition and Exercise Physiology (Z.I.G., J.P.), University of Missouri, Columbia.
⁵ Dalton Cardiovascular Research Center (Z.I.G., L.A.M.-.L., J.P.), University of Missouri, Columbia.
⁶ School of Physical Education and Sport, University of São Paulo, Brazil (C.E.N.).

No abstract available

Keywords: endothelial function; exercise training; heart failure; sympathetic activity; vasoconstriction.

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