Need for Speed: From Human SARS-CoV-2 Samples to Protective and Efficacious Antibodies in Weeks

M Gordon Joyce; Adam K Wheatley; Kayvon Modjarrad

doi:10.1016/j.cell.2020.06.017

Need for Speed: From Human SARS-CoV-2 Samples to Protective and Efficacious Antibodies in Weeks

Cell. 2020 Jul 9;182(1):7-9. doi: 10.1016/j.cell.2020.06.017.

Authors

M Gordon Joyce¹, Adam K Wheatley², Kayvon Modjarrad³

Affiliations

¹ Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. Electronic address: gjoyce@eidresearch.org.
² Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
³ Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.

Abstract

The emergence of SARS-CoV-2 has driven a global research effort to identify medical countermeasures at an unprecedented pace. In this issue of Cell, Cao et al. identify thousands of SARS-CoV-2 neutralizing antibodies from convalescent donors. The authors improve our understanding of immunity against the coronavirus spike glycoprotein and detail novel pathways to rapidly identify and characterize protective monoclonal antibodies.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Antibodies, Viral
Betacoronavirus
COVID-19
Coronavirus Infections*
Humans
Pandemics*
Pneumonia, Viral*
SARS-CoV-2
Severe acute respiratory syndrome-related coronavirus / immunology*

Substances

Antibodies, Viral