Cognitive evolutionary therapy versus standard cognitive therapy for depression: A single-blinded randomized clinical trial

J Clin Psychol. 2020 Oct;76(10):1818-1831. doi: 10.1002/jclp.22991. Epub 2020 Jun 30.

Abstract

Objective: To compare the efficacy of cognitive evolutionary therapy (CET) with cognitive therapy (CT) for depression.

Methods: Ninety-seven participants (78 females/19 males) were randomized to a single-blinded controlled trial (CET: n = 51 vs. CT: n = 46). Assessments were conducted at baseline, Sessions 4 and 8, posttreatment, and 3-month follow-up. Clinical diagnoses were made with Structured Clinical Interview for DSM-IV (SCID) and self-reports for depression and secondary outcomes.

Results: Although both groups showed significant reductions in depressive symptomatology, the overall Time × Treatment group interaction in the intent to treat analysis was not significant (p = .770, posttreatment: d = 0.39). However, CET was superior to CT at increasing engagement in social and enjoyable activities (p = .040, posttreatment: d = 0.83, p = .040) and showed greater reductions than the CT group in behavioral inhibition/avoidance (p = .047, d = 0.62). The between-group differences generally diminished at the 3-month follow-up.

Conclusions: CET is a novel therapy for depression that may add therapeutic benefits beyond those of CT.

Keywords: Darwinian psychiatry; cognitive therapy; depression; evolutionary psychopathology; evolutionary therapy; randomized trial.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cognitive Behavioral Therapy / methods*
  • Depression / psychology
  • Depression / therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Single-Blind Method
  • Treatment Outcome