Two cases of pseudoxanthoma elasticum are described in brothers who both presented with gastric haemorrhage. The angiographic findings demonstrate the spectrum of vascular abnormalities seen in this condition. Although rare, the combination of angiomatous malformations, aneurysmal dilatation, narrowing and/or occlusion of visceral or peripheral arteries in a relatively young patient with abdominal pain or gastrointestinal bleeding, should alert the radiologist to the diagnosis. Examination will usually reveal the characteristic xanthomatous papular rash and retinal angioid streaks which confirm the diagnosis.