The parent drugs chloroquine and hydroxychloroquine do not inhibit human CYP3A activity in vitro

Eur J Clin Pharmacol. 2020 Oct;76(10):1481-1482. doi: 10.1007/s00228-020-02928-7. Epub 2020 Jun 18.
No abstract available

Publication types

  • Comparative Study
  • Letter

MeSH terms

  • Antirheumatic Agents / pharmacology
  • Chloroquine / pharmacology*
  • Cytochrome P-450 CYP3A / drug effects*
  • Cytochrome P-450 CYP3A / metabolism
  • Drug Interactions
  • Humans
  • Hydroxychloroquine / pharmacology*
  • In Vitro Techniques

Substances

  • Antirheumatic Agents
  • Hydroxychloroquine
  • Chloroquine
  • Cytochrome P-450 CYP3A
  • CYP3A4 protein, human