COVID-19 Clinical Trials: A Teachable Moment for Improving Our Research Infrastructure and Relevance

Stephen E Kimmel; Robert M Califf; Natalie E Dean; Steven N Goodman; Elizabeth L Ogburn

doi:10.7326/M20-2959

COVID-19 Clinical Trials: A Teachable Moment for Improving Our Research Infrastructure and Relevance

Ann Intern Med. 2020 Oct 20;173(8):652-653. doi: 10.7326/M20-2959. Epub 2020 Jun 16.

Authors

Stephen E Kimmel¹, Robert M Califf², Natalie E Dean³, Steven N Goodman⁴, Elizabeth L Ogburn⁵

Affiliations

¹ Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (S.E.K.).
² Verily Life Sciences and Google Health, South San Francisco, California (R.M.C.).
³ University of Florida College of Public Health and Health Professions and the College of Medicine, Gainesville, Florida (N.E.D.).
⁴ Stanford University School of Medicine, Stanford, California (S.N.G.).
⁵ Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (E.L.O.).

Abstract

The authors posit the need for rapid evaluation of therapies for COVID-19 as an inflection point spurring a much-needed rethinking of our research enterprise.

Publication types

Editorial

MeSH terms

Betacoronavirus*
COVID-19
Clinical Trials as Topic / methods*
Coronavirus Infections / epidemiology
Coronavirus Infections / therapy*
Disease Management*
Humans
Pandemics*
Pneumonia, Viral / epidemiology
Pneumonia, Viral / therapy*
SARS-CoV-2

Grants and funding

R01 AI139761/AI/NIAID NIH HHS/United States