Clinical and radiological characteristics of pediatric patients with COVID-19: focus on imaging findings

Jpn J Radiol. 2020 Oct;38(10):987-992. doi: 10.1007/s11604-020-01003-6. Epub 2020 Jun 13.

Abstract

Purpose: CT imaging has been a detrimental tool in the diagnosis of COVID-19, but it has not been studied thoroughly in pediatric patients and its role in diagnosing COVID-19.

Methods: 27 pediatric patients with COVID-19 pneumonia were included. CT examination and molecular assay tests were performed from all participants. A standard checklist was utilized to extract information, and two radiologists separately reviewed the CT images.

Results: The mean age of patients was 4.7 ± 4.16 (mean ± SD) years. Seventeen patients were female, and ten were male. The most common imaging finding was ground-glass opacities followed by consolidations. Seven patients had a single area of involvement, five patients had multiple areas of involvement, and four patients had diffuse involvement. The sensitivity of CT imaging in diagnosing infections was 66.67%. Also, some uncommon imaging findings were seen, such as a tree-in-bud and lung collapse.

Conclusion: CT imaging shows less involvement in pediatric compared to adult patients, due to pediatric patients having a milder form of the disease. CT imaging also has a lower sensitivity in detecting abnormal lungs compared to adult patients. The most common imaging findings are ground-glass opacities and consolidations, but other non-common imaging findings also exist.

Keywords: COVID-19; Coronavirus infections; Pediatrics; SARS-CoV-2; Tomography; X-ray computed.

MeSH terms

  • Betacoronavirus*
  • COVID-19
  • Child
  • Child, Preschool
  • Coronavirus Infections / diagnostic imaging*
  • Coronavirus Infections / physiopathology*
  • Female
  • Humans
  • Lung / diagnostic imaging*
  • Male
  • Pandemics
  • Pediatrics / methods
  • Pneumonia, Viral / diagnostic imaging*
  • Pneumonia, Viral / physiopathology*
  • SARS-CoV-2
  • Tomography, X-Ray Computed / methods*