Clinical, Dermoscopic and In-Vivo Reflectance Confocal Microscopy Evaluation of a Case of Graham Little-Piccardi-Lassueur Syndrome Successfully Treated with Narrowband-UVB Phototherapy

Mariachiara Arisi; Alessandra Gelmetti; Arianna Zanca; Mariateresa Rossi; Luisa Lorenzi; Paolo Incardona; Piergiacomo Calzavara-Pinton; Marina Venturini

doi:10.1007/s13555-020-00410-x

Clinical, Dermoscopic and In-Vivo Reflectance Confocal Microscopy Evaluation of a Case of Graham Little-Piccardi-Lassueur Syndrome Successfully Treated with Narrowband-UVB Phototherapy

Dermatol Ther (Heidelb). 2020 Aug;10(4):887-892. doi: 10.1007/s13555-020-00410-x. Epub 2020 Jun 12.

Authors

Mariachiara Arisi¹, Alessandra Gelmetti², Arianna Zanca², Mariateresa Rossi², Luisa Lorenzi³, Paolo Incardona³, Piergiacomo Calzavara-Pinton², Marina Venturini²

Affiliations

¹ Department of Dermatology, University of Brescia, ASST Spedali Civili of Brescia, Brescia, Italy. mariachiara.arisi@gmail.com.
² Department of Dermatology, University of Brescia, ASST Spedali Civili of Brescia, Brescia, Italy.
³ Pathology Department, University of Brescia, ASST Spedali Civili di Brescia, Brescia, Italy.

Abstract

Graham Little-Piccardi-Lassueur syndrome (GLPLS) is a rare variant of lichen planopilaris, characterized by a triad of clinical signs including follicular spinous papules on the body area, scarring alopecia of the scalp and non-scarring alopecia of the groin and/or axilla. To date, fewer than 50 cases have been described in the literature. We first report a case of GLPLS investigated with non-invasive techniques such as dermoscopy and in vivo reflectance confocal microscopy (RCM) and successfully treated with narrowband-UVB (NB-UVB) phototherapy.

Keywords: Cicatricial alopecia; Graham Little-Piccardi-Lassueur syndrome; Lichen spinulosus; NB-UVB phototherapy.