A new duplication at the C4B locus associated with the HLA-Aw68, Cw8, Bw65 haplotype

J Immunogenet. 1988 Aug;15(4):239-41. doi: 10.1111/j.1744-313x.1988.tb00426.x.

Abstract

A family with a cross-over between HLA-B and HLA-DR was analysed for its complement alleles. This allowed location of the cross-over between HLA-B and C4. Furthermore, the same family showed a previously undescribed duplication at the C4B locus (C4B* 2,2) that was associated with the HLA-Aw68, Cw8, Bw65, C2*1, Bf*S, C4A*2, DR7, DQw2 haplotype.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alleles*
  • Child
  • Crossing Over, Genetic
  • Electrophoresis
  • Female
  • HLA-A Antigens / analysis
  • HLA-A Antigens / genetics*
  • HLA-B Antigens / analysis
  • HLA-B Antigens / genetics*
  • HLA-C Antigens / analysis
  • HLA-C Antigens / genetics*
  • Haplotypes*
  • Humans
  • Male

Substances

  • HLA-A Antigens
  • HLA-A*68 antigen
  • HLA-B Antigens
  • HLA-C Antigens
  • HLA-C*08 antigen