FDG PET/CT in a Patient With Mantle Cell Lymphoma and COVID-19: Typical Findings

Clin Nucl Med. 2020 Jul;45(7):e305-e306. doi: 10.1097/RLU.0000000000003113.

Abstract

A 52-year-old woman with no medical history was admitted on March 18, 2020, presenting since 3 days asthenia, abdominal pain, and dry cough but no fever. Adenomegalies, splenomegaly, leukocytosis, and elevated LDH suggested mature lymphoproliferation. Considering the current health context, an RT-PCR testing for COVID-19 (coronavirus disease 2019) was performed and found to be positive. Early chest CT showed no sign of pulmonary infection but multiple adenomegalies. An F-FDG PET/CT performed 5 days later to assess the extent of the hemopathy revealed the apparition of FDG-avid bilateral ground glass and subpleural curvilinear opacities suggesting COVID-19-associated pneumopathy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • COVID-19
  • COVID-19 Testing
  • Clinical Laboratory Techniques
  • Coronavirus Infections / complications
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / diagnostic imaging*
  • Coronavirus Infections / pathology
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology
  • Lymphoma, Mantle-Cell / complications
  • Lymphoma, Mantle-Cell / diagnostic imaging*
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / complications
  • Pneumonia, Viral / diagnostic imaging*
  • Pneumonia, Viral / pathology
  • Positron Emission Tomography Computed Tomography*
  • Radiopharmaceuticals

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18