A call to research: the relationship between SARS-2-CoV, ACE 2 and antihypertensives

Pathog Glob Health. 2020 May 18;114(4):165-167. doi: 10.1080/20477724.2020.1765650. Epub 2020 May 25.

Authors

Antonio Cassone¹, Donatella Gucciardo², Roberto Cauda³

Affiliations

¹ Polo of Innovation of Genomics, Genetics and Biology, University of Siena , Rome, Italy.
² Public Health District of Palermo, Pediatric Unit, The Catholic University, IRRCS Policlinico Gemelli , Rome, Italy.
³ Department of Infectious Disease, The Catholic University, IRRCS Policlinico Gemelli , Rome, Italy.

No abstract available

MeSH terms

Angiotensin-Converting Enzyme 2
Angiotensin-Converting Enzyme Inhibitors / pharmacology
Animals
Antihypertensive Agents / pharmacology*
Blood Pressure / drug effects
COVID-19
Coronavirus Infections / drug therapy
Coronavirus Infections / genetics
Coronavirus Infections / metabolism*
Coronavirus Infections / virology
Humans
Lung / drug effects
Lung / metabolism
Lung / virology
Mice
Pandemics
Peptidyl-Dipeptidase A / genetics
Peptidyl-Dipeptidase A / metabolism*
Pneumonia, Viral / drug therapy
Pneumonia, Viral / genetics
Pneumonia, Viral / metabolism*
Pneumonia, Viral / virology
Protein Binding / drug effects
Severe acute respiratory syndrome-related coronavirus / drug effects*
Severe acute respiratory syndrome-related coronavirus / genetics
Severe acute respiratory syndrome-related coronavirus / metabolism
Severe acute respiratory syndrome-related coronavirus / physiology
Spike Glycoprotein, Coronavirus / genetics
Spike Glycoprotein, Coronavirus / metabolism

Substances

Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2
Peptidyl-Dipeptidase A
ACE2 protein, human
Ace2 protein, mouse
Angiotensin-Converting Enzyme 2