Influenza Vaccine Does Not Increase the Risk of Coronavirus or Other Noninfluenza Respiratory Viruses: Retrospective Analysis From Canada, 2010-2011 to 2016-2017

Clin Infect Dis. 2020 Nov 19;71(16):2285-2288. doi: 10.1093/cid/ciaa626.

Abstract

Influenza vaccine effectiveness against influenza and noninfluenza respiratory viruses (NIRVs) was assessed by test-negative design using historic datasets of the community-based Canadian Sentinel Practitioner Surveillance Network, spanning 2010-2011 to 2016-2017. Vaccine significantly reduced the risk of influenza illness by >40% with no effect on coronaviruses or other NIRV risk.

Keywords: coronavirus; influenza; nonspecific immunity; respiratory viruses; vaccine effectiveness.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Canada / epidemiology
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / etiology
  • Female
  • Humans
  • Immunogenicity, Vaccine
  • Infant
  • Influenza Vaccines / administration & dosage
  • Influenza Vaccines / immunology*
  • Influenza, Human / epidemiology
  • Influenza, Human / prevention & control*
  • Male
  • Middle Aged
  • Respiratory Tract Infections / prevention & control
  • Respiratory Tract Infections / virology*
  • Retrospective Studies
  • Risk Factors
  • Seasons
  • Sentinel Surveillance
  • Young Adult

Substances

  • Influenza Vaccines