Durable biochemical response following adrenal metastasectomy for oligometastatic castrate-resistant prostate cancer

Urol Case Rep. 2020 Apr 29:32:101229. doi: 10.1016/j.eucr.2020.101229. eCollection 2020 Sep.

Abstract

A 77 year-old man was referred to Urology with an enlarging left adrenal mass after treatment with androgen deprivation therapy for metastatic castrate-resistant prostate cancer. He underwent a robotic-assisted left radical adrenalectomy, with pathology revealing metastatic adenocarcinoma consistent with a primary prostate adenocarcinoma. The patient had a durable oncological response to metastasectomy with no evidence of biochemical or radiological recurrence after 5 years of follow-up. Adrenal metastases from prostate cancer are extremely rare, representing only 1% of metastatic cases. Surgical resection of oligometastatic prostate cancer recurrences may be considered in select patients and may improve progression-free survival.

Keywords: Adrenal metastasis; Adrenalectomy; Oligometastasis; Prostate cancer.

Publication types

  • Case Reports