Primary amenorrhea in females attending gynaecological outpatient of a tertiary care hospital at Peshawar

J Pak Med Assoc. 2020 May;70(5):888-891. doi: 10.5455/JPMA.24317.

Abstract

Objective: To determine the aetiological factors of amenorrhea.

Methods: The pilot cross-sectional study was conducted in Government Naserullah Khan Babar Memorial Hospital, Peshawar, Pakistan, from January 2015 to December 2017, and comprised amenorrhea cases. Cases were analysed according to their clinical profile, ultrasound findings and biochemical tests. Data was analysed using SPSS 20.

Results: There were 100 patients with a mean age of 22.17±5.52 years (range: 14-36 years). Anatomical defects were the most common cause in 60(60%) patients. Imperforate hymen and transverse vaginal septum were found in 7(7%), 7(7%) patients each, while mullerian abnormalities were found in 46(46%) patients. Hypergonadotropic hypogonadism and polycystic ovarian syndrome were found in 17(17%) patients each.

Conclusions: Anatomical defects were found to be the most common cause among amenorrhea patients.

Keywords: Primary amenorrhea, Mullerian anomalies, Hypogonadotropic hypogonadism, Hypergonadotropic hypogonadism, Primary ovarian failure, Hyperprolactinemia..

MeSH terms

  • Adolescent
  • Adult
  • Amenorrhea* / diagnosis
  • Amenorrhea* / epidemiology
  • Amenorrhea* / etiology
  • Amenorrhea* / psychology
  • Cross-Sectional Studies
  • Female
  • Genitalia, Female / diagnostic imaging*
  • Gynecology / methods
  • Humans
  • Hypogonadism* / complications
  • Hypogonadism* / diagnosis
  • Hypogonadism* / epidemiology
  • Pakistan / epidemiology
  • Physician's Role
  • Pilot Projects
  • Polycystic Ovary Syndrome* / complications
  • Polycystic Ovary Syndrome* / diagnosis
  • Polycystic Ovary Syndrome* / epidemiology
  • Psychosocial Support Systems
  • Tertiary Care Centers
  • Urogenital Abnormalities* / classification
  • Urogenital Abnormalities* / complications
  • Urogenital Abnormalities* / diagnosis
  • Urogenital Abnormalities* / epidemiology