1 From the School of Anaesthesia and Intensive Care, University of Modena and Reggio Emilia (AB), Anaesthesia and Intensive Care, Policlinico Teaching Hospital, Azienda Ospedaliero-Universitaria di Modena (GM) and Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy (EG).