Laparoscopic gastrectomy with D2 lymphadenectomy for gastric cancer: initial Egyptian experience at the National Cancer Institute

J Egypt Natl Canc Inst. 2020 Feb 18;32(1):10. doi: 10.1186/s43046-020-00023-7.

Abstract

Background: Laparoscopic gastrectomy has been used as a superior alternative to open gastrectomy for the treatment of early gastric cancer. However, the application of laparoscopic D2 lymphadenectomy remains controversial. This study aimed to evaluate the feasibility and outcomes of laparoscopic gastrectomy with D2 lymphadenectomy for gastric cancer.

Results: Between May 2016 and May 2018, twenty-five consecutive patients with gastric cancer underwent laparoscopic D2 gastrectomy: eighteen patients (72%) underwent distal gastrectomy, four patients (16%) underwent total gastrectomy, and three patients (12%) underwent proximal gastrectomy. The median number of lymph nodes retrieved was 18 (5-35). A positive proximal margin was detected in 2 patients (8%). The median operative time and amount of blood loss were 240 min (200-330) and 250 ml (200-450), respectively. Conversion to an open procedure was performed in seven patients (28%). The median hospital stay period was 8 days (6-30), and the median time to start oral fluids was 4 days (3-30). Postoperative complications were detected in 4 patients (16%). There were two cases of mortality (8%) in the postoperative period, and two patients required reoperation (8%).

Conclusions: Laparoscopic gastrectomy with D2 lymphadenectomy can be carried out safely and in accordance with oncologic principles.

Keywords: D2 lymphadenectomy; Gastric cancer; Laparoscopic gastrectomy.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Blood Loss, Surgical / statistics & numerical data
  • Chemotherapy, Adjuvant / methods
  • Conversion to Open Surgery / statistics & numerical data
  • Egypt / epidemiology
  • Feasibility Studies
  • Female
  • Gastrectomy / adverse effects
  • Gastrectomy / methods*
  • Hospital Mortality
  • Humans
  • Laparoscopy / adverse effects
  • Laparoscopy / methods*
  • Length of Stay / statistics & numerical data
  • Lymph Node Excision / adverse effects
  • Lymph Node Excision / methods*
  • Lymph Nodes / pathology
  • Lymph Nodes / surgery
  • Male
  • Middle Aged
  • Neoadjuvant Therapy / methods
  • Operative Time
  • Pilot Projects
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Response Evaluation Criteria in Solid Tumors
  • Stomach Neoplasms / mortality
  • Stomach Neoplasms / pathology
  • Stomach Neoplasms / therapy*