Impedimetric aptamer-based biosensors show high potential for handheld devices and point-of-care tests. In this review, we report on recent advances in aptamer-based impedimetric biosensors for applications in biotechnology. We detail on analytes relevant in medical and environmental biotechnology as well as food control, for which aptamer-based impedimetric biosensors were developed. The reviewed biosensors are examined for their performance, including sensitivity, selectivity, response time, and real sample validation. Additionally, the benefits and challenges of impedimetric aptasensors are summarized.
Keywords: Aptamer; Aptasensor; Bacteria; Biomarker; Biosensor; Cancer; Contaminants; Diagnostics; Disease; Drug; Environmental; Food industry; Health care; Impedance; Infection; Monitoring; Pathogen; Point-of-care; Serum; Therapy; Toxins; Tumor marker; Virus.