We herein report a case involving a 59-year-old man with right lung and mediastinal lymph node metastases from renal cell carcinoma. After cytoreductive nephrectomy without neoadjuvant therapy, he achieved spontaneous regression. The regression was maintained 3 years after the operation. We immunohistochemically examined the surgical specimens and considered the possible mechanism underlying this phenomenon.
Keywords: Cytoreductive nephrectomy; Renal cell carcinoma; Spontaneous regression.
© 2020 Published by Elsevier Inc.