There is a new concept of diabetes as a "comprehensive nutrition disorder", caused due to both insulin and glucagon dysregulation. Dysregulated glucagon secretion in α-cells exacerbates multiple metabolic disorders: glycemic control and amino acid metabolism, together with insulin deficiency.
© 2020 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.