Twelve Weeks of Reversed Umbilical Flow in a Fetal Growth Restriction Case Associated with Severe Periconceptional Maternal Anemia

J Ultrasound Med. 2020 Sep;39(9):1873-1875. doi: 10.1002/jum.15274. Epub 2020 Apr 16.

Abstract

We present a case of a patient diagnosed with severe intrauterine growth restriction and periconceptional severe anemia, where the fetal well-being features, including reversal of umbilical artery end-diastolic flow and abnormal cerebroplacental ratio, remained stationary for 12 weeks. We are not aware of reports with similar findings, and the professionals should take into consideration the possibility of a "frozen" fetal well-being for a long time. Possibly, in our case, the evolution may be due to the prompt correction of the chronic severe maternal anemia. This approach may offer the opportunity to prolong the pregnancy, even in cases with apparently imminent delivery, as the association of reversal of umbilical artery end-diastolic flow.

Keywords: anemia; congenital malformation; fetal distress; intrauterine growth restriction; reversed umbilical flow.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Anemia* / diagnostic imaging
  • Female
  • Fetal Growth Retardation* / diagnostic imaging
  • Humans
  • Pregnancy
  • Pulsatile Flow
  • Ultrasonography, Doppler
  • Ultrasonography, Prenatal
  • Umbilical Arteries / diagnostic imaging