Benign focal liver lesions masquerading as primary liver cancers on MRI

Diagn Interv Radiol. 2020 May;26(3):168-175. doi: 10.5152/dir.2019.19235.

Abstract

Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the most common primary liver malignancies. HCC and ICC have characteristic imaging findings, but a number of benign entities can appear similar and can cause diagnostic dilemma. Ideally, accurate and timely diagnosis of these conditions can help the patient to avoid a needle biopsy or even unnecessary treatment. In this article, we present various benign liver lesions that display imaging characteristics that are similar to HCC and ICC on magnetic resonance imaging (MRI) and discuss salient features that may assist in accurate diagnosis.

Publication types

  • Review

MeSH terms

  • Adenoma, Bile Duct / diagnostic imaging
  • Adenoma, Bile Duct / pathology
  • Adenoma, Liver Cell / diagnostic imaging*
  • Adenoma, Liver Cell / pathology
  • Adult
  • Aged
  • Angiomyolipoma / diagnostic imaging
  • Angiomyolipoma / pathology
  • Bile Duct Neoplasms / pathology
  • Carcinoma, Hepatocellular / diagnostic imaging*
  • Cholangiocarcinoma / diagnostic imaging*
  • Contrast Media
  • Cysts / diagnostic imaging
  • Cysts / pathology
  • Diagnosis, Differential
  • Female
  • Granuloma, Plasma Cell / diagnostic imaging
  • Granuloma, Plasma Cell / pathology
  • Hemangioma / diagnostic imaging
  • Hemangioma / pathology
  • Histiocytoma, Benign Fibrous / diagnostic imaging
  • Histiocytoma, Benign Fibrous / pathology
  • Humans
  • Liver Abscess / diagnostic imaging
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / pathology
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Portasystemic Shunt, Surgical / statistics & numerical data
  • Splenosis / diagnostic imaging
  • Splenosis / pathology

Substances

  • Contrast Media