[Complex morphological (cytological, histological) diagnostics of desmoid fibroma associated with a breast implant (case report from practice)]

Klin Lab Diagn. 2020;65(4):228-230. doi: 10.18821/0869-2084-2020-65-4-228-230.
[Article in Russian]

Abstract

A rare clinical observation of desmoid fibroma associated with a breast implant is presented. When making a morphological (cytological, histological) diagnosis at the light-optical level before surgery, a differential morphological diagnosis was performed between cicatricial changes, the stromal component of the phyloid tumor and desmoid fibroma. Only immunohistochemistry allowed us to establish a diagnosis of desmoid fibroma, since tumor cells expressed diffusely SMA, focally desmin, and most importantly, ß-catenin expression was observed in some cells.

Keywords: cytology; desmoid fibroma; histology; immunohistochemistry; implant; mammary gland.

Publication types

  • Case Reports

MeSH terms

  • Breast Implants / adverse effects*
  • Cicatrix
  • Desmoid Tumors / etiology*
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry