Silver-catalyzed direct C-H oxidative carbamoylation of quinolines with oxamic acids

Org Biomol Chem. 2020 Apr 8;18(14):2747-2757. doi: 10.1039/d0ob00358a.

Abstract

A silver-catalyzed efficient and direct C-H carbamoylation of quinolines with oxamic acids to access carbamoylated quinolines has been developed through oxidative decarboxylation reaction. The reaction proceeds smoothly over a broad range of substrates with excellent functional group tolerance and excellent yields under mild conditions.

Publication types

  • Research Support, Non-U.S. Gov't