Cardiolipin's Remodeling Rules Revealed: The Role of the Cellular Lipidome

Olivia L Sniezek; Arianna F Anzmann; Steven M Claypool; Hilary J Vernon

doi:10.1016/j.celrep.2020.03.010

Cardiolipin's Remodeling Rules Revealed: The Role of the Cellular Lipidome

Cell Rep. 2020 Mar 24;30(12):3949-3950. doi: 10.1016/j.celrep.2020.03.010.

Authors

Olivia L Sniezek¹, Arianna F Anzmann¹, Steven M Claypool², Hilary J Vernon¹

Affiliations

¹ Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
² Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: sclaypo1@jhmi.edu.

PMID: 32209457
DOI: 10.1016/j.celrep.2020.03.010

Abstract

In this issue of Cell Reports, Oemer et al. (2020) define the acyl chain composition of cardiolipin and other lipid classes in murine tissues. They then employ artificial neural networks to predict mechanisms that govern cardiolipin tissue specificity, with implications for understanding cellular pathogenesis in human disease.

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MeSH terms

Animals
Cardiolipins*
Humans
Lipidomics*
Mice
Mitochondria
Phospholipids

Substances

Cardiolipins
Phospholipids