[Analysis of prognosis and scoring systems in patients with liver failure combined with fungal infection]

Y Wang; X Xu; J J Tong; X Y Mu; J Chen; X R Zhai; J H Hu

doi:10.3760/cma.j.issn.1007-3418.2020.02.014

[Analysis of prognosis and scoring systems in patients with liver failure combined with fungal infection]

Zhonghua Gan Zang Bing Za Zhi. 2020 Feb 20;28(2):168-171. doi: 10.3760/cma.j.issn.1007-3418.2020.02.014.

[Article in Chinese]

Authors

Y Wang¹, X Xu², J J Tong², X Y Mu³, J Chen¹, X R Zhai³, J H Hu⁴

Affiliations

¹ Medical School of Chinese PLA, Beijing 100853, China.
² Liver Failure Treatment and Research Center, the Fifth Medical Center of PLA General Hospital, Beijing 100039, China.
³ Peking University 302 Clinical Medical School, Beijing 100039, China.
⁴ Medical School of Chinese PLA, Beijing 100853, China; Liver Failure Treatment and Research Center, the Fifth Medical Center of PLA General Hospital, Beijing 100039, China.

PMID: 32164071
DOI: 10.3760/cma.j.issn.1007-3418.2020.02.014

Abstract

收集2008年1月至2017年12月解放军总医院第五医学中心收治的372例肝衰竭合并真菌感染患者临床资料，探讨肝衰竭合并真菌感染患者预后的影响因素，分析CLIF-C ACLF、CLIF-SOFA、SOFA、MELD、MELD-NA及CTP评分系统对预测患者短期病死率的价值。结果显示影响肝衰竭合并真菌感染患者90 d预后的独立危险因素有年龄、抗真菌疗效、肝性脑病（HE）、总胆红素（TBil）及国际标准化比值（INR）；6种预后评分系统中CLIF-C ACLF评分对患者短期病死率预测价值最高。.

Keywords: Fungal infection; Liver failure; Prognosis; Prognostic scoring system.

MeSH terms

Coinfection
Decision Support Techniques
Humans
Liver Failure / diagnosis*
Liver Failure / etiology
Mycoses / diagnosis*
Predictive Value of Tests
Prognosis
Retrospective Studies
Severity of Illness Index

Grants and funding

D171100003117005/Major Projects of Beijing Municipal Science and Technology Commission's 2017 Science and Technology Plan