In vivo expansion of functional human hematopoietic stem progenitor cells by butyzamide

Int J Hematol. 2020 May;111(5):739-741. doi: 10.1007/s12185-020-02849-2. Epub 2020 Mar 12.

Authors

Masatoshi Sakurai¹, Hiroshi Takemoto^{2

3}, Takehiko Mori¹, Shinichiro Okamoto¹, Satoshi Yamazaki⁴

Affiliations

¹ Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, 160-8582, Japan.
² Department of Neuroscience, Drug Discovery and Disease Research Laboratory, Shionogi, Osaka, 541-0825, Japan.
³ Graduate School of Pharmaceutical Sciences, Business-Academia Collaborative Laboratory (Shionogi), The University of Tokyo, Tokyo, Japan.
⁴ Division of Stem Cell Biology, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan. y-sato4@ims.u-tokyo.ac.jp.

PMID: 32162097
DOI: 10.1007/s12185-020-02849-2

No abstract available

Publication types

Letter

MeSH terms

ADP-ribosyl Cyclase 1
Anemia, Aplastic / drug therapy
Animals
Antigens, CD34
Bone Marrow Cells
Cell Differentiation / drug effects*
Hematopoietic Stem Cell Transplantation*
Hematopoietic Stem Cells / physiology*
Humans
Leukocyte Common Antigens
Methacrylates / pharmacology*
Methacrylates / therapeutic use
Mice, Inbred NOD
Platelet Membrane Glycoprotein IIb
Receptors, Thrombopoietin / agonists*
Thiazoles / pharmacology*
Thiazoles / therapeutic use

Substances

Antigens, CD34
Methacrylates
Platelet Membrane Glycoprotein IIb
Receptors, Thrombopoietin
Thiazoles
butyzamide
Leukocyte Common Antigens
ADP-ribosyl Cyclase 1