Assessment of the many faces of PsA: single and composite measures in PsA clinical trials

Rheumatology (Oxford). 2020 Mar 1;59(Suppl 1):i29-i36. doi: 10.1093/rheumatology/kez305.

Abstract

PsA is a complex, heterogeneous disease that can place a large burden on patients' psychological and physical well-being. The multifaceted nature of PsA poses a significant assessment challenge, both in randomized control trials and in clinical practice. In recent years, there has been much progress in the development of unidimensional and composite measures of disease activity, as well as of questionnaires that capture the patient's perspective of the condition. Despite these advances, there remains uncertainty around which tools to implement within a research setting. This review aims to summarize the currently available clinical and patient-derived assessment tools, providing a practical and informative resource for the assessment of PsA. This review will also explore recent advancements in digital approaches to the assessment of rheumatological conditions. This will highlight the potential for digitalization in the assessment and monitoring of PsA, outlining innovative means of capturing disease activity and treatment response.

Keywords: composite measures; disease activity; health information technology; impact of disease; mobile health; outcome measures; patient perspective; psoriatic arthritis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Arthritis / complications
  • Arthritis, Psoriatic / drug therapy*
  • Arthritis, Psoriatic / pathology
  • Arthritis, Psoriatic / psychology*
  • Cost of Illness
  • Enthesopathy / complications
  • Humans
  • Medical Informatics / instrumentation*
  • Outcome Assessment, Health Care
  • Pain Measurement / statistics & numerical data
  • Quality of Life
  • Randomized Controlled Trials as Topic
  • Spondylarthropathies / complications
  • Surveys and Questionnaires / statistics & numerical data*
  • Telemedicine / methods