Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features

Acta Neuropathol. 2020 May;139(5):953-957. doi: 10.1007/s00401-020-02144-8. Epub 2020 Mar 10.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Female
  • Genetic Predisposition to Disease / genetics*
  • Germ-Line Mutation / genetics
  • Glioma / genetics
  • Glioma / pathology*
  • Humans
  • Li-Fraumeni Syndrome / genetics*
  • Li-Fraumeni Syndrome / pathology*
  • Male
  • Tumor Suppressor Protein p53 / genetics
  • Young Adult

Substances

  • Tumor Suppressor Protein p53