Stroke and Bleeding Risk Assessments in Patients With Atrial Fibrillation: Concepts and Controversies

Wern Yew Ding; Stephanie Harrison; Dhiraj Gupta; Gregory Y H Lip; Deirdre A Lane

doi:10.3389/fmed.2020.00054

Stroke and Bleeding Risk Assessments in Patients With Atrial Fibrillation: Concepts and Controversies

Front Med (Lausanne). 2020 Feb 21:7:54. doi: 10.3389/fmed.2020.00054. eCollection 2020.

Authors

Wern Yew Ding¹, Stephanie Harrison¹, Dhiraj Gupta¹, Gregory Y H Lip^{1

2}, Deirdre A Lane^{1

2}

Affiliations

¹ Liverpool Centre for Cardiovascular Science, Liverpool Heart and Chest Hospital, University of Liverpool, Liverpool, United Kingdom.
² Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

Abstract

Risk assessments are an important element in the management of patients with atrial fibrillation (AF). In this review, we aim to discuss the concepts and controversies surrounding the various risk factors for stroke and bleeding in AF. Indeed, there are a variety of clinical, electrical, biological, and genetic markers to guide stroke and bleeding risk assessments in AF. The more common factors have been used to formulate risk stratification scores. Some risk factors have shown promise, but others remain less well-defined. Our aim is to discuss concepts and controversies surrounding current evidence of risk factors for stroke and bleeding assessments in AF.

Keywords: atrial fibrillation; bleeding; risk assessment; risk factors; stroke.

Publication types

Review