Time Intervals for Direct Versus Transfer Cases of Thrombectomy for Stroke in a Primarily Rural System of Care

J Stroke Cerebrovasc Dis. 2020 Jun;29(6):104689. doi: 10.1016/j.jstrokecerebrovasdis.2020.104689. Epub 2020 Mar 6.

Abstract

Background: Early treatment is the key to a successful recovery for ischemic stroke patients. From time of onset, a patient's chances of permanent disability only increase until they can receive reperfusion intervention.

Objective: We sought to identify potential delays that occur during evaluation and treatment of patients in a rural regional health system.

Methods: We conducted a single-center retrospective review of all patients that arrived at our comprehensive stroke center (CSC) between July 2011 and March 2017, and received thrombectomy, with or without prior treatment with intravenous recombinant tissue plasminogen activator.

Results: One hundred and fifty-four patients met our criteria for inclusion. Patients were divided into 2 groups: Direct (patients brought to our CSC from scene) and Transfer (patients taken to an outside hospital then transferred to our CSC). The median time to CSC for Direct patients was 82 (range: 15-863) minutes after onset of symptoms, compared to 237 (range: 98-1215) minutes for the Transfer group. The median time for Transfer patients to reach an outside hospital was 74 (range: 5-840) minutes, with an additional average time of 90 minutes in the outside hospital prior to transferred to our CSC.

Conclusions: Based on our findings, patients brought directly to our CSC saved a significant amount of time, which may improve functional outcomes. Both groups (Direct and Transfer) spent a similar amount of time between last known normal and emergency medical services arrival, highlighting the need for increased awareness among the public to activate the stroke system of care.

Keywords: Stroke; regional; rural; thrombectomy; transfer; transport.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Brain Ischemia / diagnosis
  • Brain Ischemia / physiopathology
  • Brain Ischemia / therapy*
  • Disability Evaluation
  • Female
  • Fibrinolytic Agents / administration & dosage
  • Humans
  • Kentucky
  • Male
  • Middle Aged
  • Patient Transfer*
  • Recovery of Function
  • Retrospective Studies
  • Rural Health Services*
  • Stroke / diagnosis
  • Stroke / physiopathology
  • Stroke / therapy*
  • Thrombectomy* / adverse effects
  • Thrombolytic Therapy
  • Time Factors
  • Time-to-Treatment*
  • Tissue Plasminogen Activator / administration & dosage
  • Treatment Outcome

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator