A case of γδ T-cell large granular lymphocytic leukemia due to a chronic active Epstein-Barr virus infection in systemic lupus erythematosus

Clin Immunol. 2020 May:214:108378. doi: 10.1016/j.clim.2020.108378. Epub 2020 Mar 4.

Authors

Momoko Okamoto¹, Kunihiro Ichinose², Shinya Sato³, Ken-Ichi Imadome⁴, Kaori Furukawa¹, Atsushi Kawakami¹

Affiliations

¹ Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
² Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. Electronic address: kichinos@nagasaki-u.ac.jp.
³ Department of Hematology, Nagasaki University Hospital, Nagasaki, Japan.
⁴ Department of Advanced Medicine for Infections, National Center for Child Health and Development, Tokyo, Japan.

PMID: 32145335
DOI: 10.1016/j.clim.2020.108378

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Viral / blood
Chronic Disease
Cyclosporine / therapeutic use
DNA, Viral / blood
Diverticulitis / complications
Drainage
Epstein-Barr Virus Infections / complications*
Female
Gene Rearrangement, T-Lymphocyte
Herpesvirus 4, Human / immunology
Humans
Immunocompromised Host
Immunosuppressive Agents / adverse effects
Immunosuppressive Agents / therapeutic use
Intraepithelial Lymphocytes / pathology*
Intraepithelial Lymphocytes / virology
Leukemia, Large Granular Lymphocytic / etiology*
Leukemia, Large Granular Lymphocytic / pathology
Leukemia, Large Granular Lymphocytic / virology
Leukopenia / drug therapy
Leukopenia / etiology
Lumbar Vertebrae
Lupus Erythematosus, Systemic / complications*
Lymphocyte Count
Middle Aged
Prednisolone / adverse effects
Prednisolone / therapeutic use
Red-Cell Aplasia, Pure / complications
Skin Diseases, Infectious / complications
Spondylitis / complications
Spondylitis / surgery

Substances

Antibodies, Viral
DNA, Viral
Immunosuppressive Agents
Cyclosporine
Prednisolone