Successful treatment of rhino-facial mucormycosis in a diabetic patient

Latifa Mtibaa; Chiraz Halwani; Makram Tbini; Siwar Boufares; Hana Souid; Raja Ben Sassi; Hedi Gharsallah; Rania Ben Mhamed; Khemaies Akkari; Boutheina Jemli

doi:10.1016/j.mmcr.2020.01.003

Successful treatment of rhino-facial mucormycosis in a diabetic patient

Med Mycol Case Rep. 2020 Jan 16:27:64-67. doi: 10.1016/j.mmcr.2020.01.003. eCollection 2020 Mar.

Authors

Affiliations

¹ Laboratory of Parasitology-Mycology, Military Hospital of Tunis, 1008, Monfleury, Tunis, Tunisia.
² Department of ENT, Military Hospital of Tunis, 1008, Monfleury, Tunis, Tunisia.
³ Department of Hyperbaric Oxygenotherapy, Military Hospital of Tunis, 1008, Monfleury, Tunis, Tunisia.

Abstract

Mucormycosis is a rapidly progressing and lethal infection caused by fungi of the order mucorales. The disease occurs mostly in patients with uncontrolled diabetes or other predisposing systemic conditions. We report a case of rhinofacial mucormycosis in a 39-year-old diabetic patient. The diagnosis was established by clinical examination, imaging, and confirmed by mycological examination. Rhizopus arrhizus was isolated. He was successfully treated with amphotericin B, surgical resection, diabetes control and hyperbaric oxygen therapy.

Keywords: Diabetes; Hyperbaric oxygen therapy; Rhinofacial mucormycosis; Rhizopus arrhizus; Treatment.

Publication types

Case Reports