Abstract
Alpha-gal-containing glycolipids activate basophils sensitized with plasma from alpha-gal allergic subjects in an IgE-dependent manner suggesting a role for glycolipid in the effector phase of IgE-mediated food allergy.
Publication types
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Letter
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Allergens / immunology
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Antigens, CD1d / metabolism
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Basophil Degranulation Test
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Basophils / immunology*
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Cell Degranulation
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Cells, Cultured
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Food Hypersensitivity / immunology*
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Glycolipids / immunology*
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Humans
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Immunoglobulin E / metabolism
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Red Meat
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alpha-Galactosidase / immunology
Substances
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Allergens
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Antigens, CD1d
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Glycolipids
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Immunoglobulin E
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GLA protein, human
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alpha-Galactosidase