High expression of myocyte enhancer factor 2C predicts poor prognosis for adult acute myeloid leukaemia with normal karyotype

Xiaoyu Xu; Zhao Zeng; Li Huo; Hong Liu; Yan Yu; Ling Zhang; Jiannong Cen; Huiying Qiu; Xiaowen Tang; Chengcheng Fu; Yue Han; Miao Miao; Zhengming Jin; Changgeng Ruan; Depei Wu; Suning Chen; Qinrong Wang; Lingzhi Yan

doi:10.1111/bjh.16418

High expression of myocyte enhancer factor 2C predicts poor prognosis for adult acute myeloid leukaemia with normal karyotype

Br J Haematol. 2020 Apr;189(1):e23-e27. doi: 10.1111/bjh.16418. Epub 2020 Feb 4.

Authors

Xiaoyu Xu^{1

2}, Zhao Zeng¹, Li Huo¹, Hong Liu^{1

3}, Yan Yu¹, Ling Zhang¹, Jiannong Cen¹, Huiying Qiu^{1

3}, Xiaowen Tang^{1

3}, Chengcheng Fu^{1

3}, Yue Han^{1

2

3}, Miao Miao^{1

3}, Zhengming Jin^{1

3}, Changgeng Ruan^{1

2

3}, Depei Wu^{1

2

3}, Suning Chen^{1

2

3}, Qinrong Wang^{1

3}, Lingzhi Yan^{1

3}

Affiliations

¹ The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Suzhou, China.
² Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.
³ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.

PMID: 32017034
DOI: 10.1111/bjh.16418

No abstract available

Keywords: acute myeloid leukemia; adult; myocyte enhancer factor 2C; normal karyotype; prognosis.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Disease-Free Survival
Female
Gene Expression Regulation, Leukemic / drug effects*
Humans
Induction Chemotherapy*
Karyotype
Leukemia, Myeloid, Acute* / blood
Leukemia, Myeloid, Acute* / drug therapy
Leukemia, Myeloid, Acute* / mortality
MEF2 Transcription Factors / blood
Male
Middle Aged
Neoplasm Proteins / blood*
Survival Rate

Substances

MEF2 Transcription Factors
MEF2C protein, human
Neoplasm Proteins

Publication types

MeSH terms

Substances

Grants and funding