Deep phenotyping detects a pathological CD4⁺ T-cell complosome signature in systemic sclerosis

Affiliations

• ¹ Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy.
• ² Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, London, UK.
• ³ Systems Cancer Immunology Lab, Comprehensive Cancer Centre, School of Cancer and Pharmaceutical Sciences, King's College London, London, UK.
• ⁴ Complement and Inflammation Research Section, NIH, NHLBI, Bethesda, MD, USA.
• ⁵ Division of Rheumatology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA.
• ⁶ School of Immunology and Microbial Sciences, King's College London, London, UK.
• ⁷ School of Biomedical Sciences, The University of Queensland, St. Lucia, QLD, Australia.
• ⁸ Systems Cancer Immunology Lab, Comprehensive Cancer Centre, School of Cancer and Pharmaceutical Sciences, King's College London, London, UK. shahram.kordasti@kcl.ac.uk.
• ⁹ Haematology Department, Guy's Hospital, London, UK. shahram.kordasti@kcl.ac.uk.
• ¹⁰ Complement and Inflammation Research Section, NIH, NHLBI, Bethesda, MD, USA. Claudia.kemper@nih.gov.
• ¹¹ School of Immunology and Microbial Sciences, King's College London, London, UK. Claudia.kemper@nih.gov.
• ¹² Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany. Claudia.kemper@nih.gov.
• ¹³ Division of Rheumatology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA. Dhourcade@wustl.edu.