X-Linked Hyper IgM Syndrome Presenting with Recurrent Tuberculosis-a Case Report

J Clin Immunol. 2020 Apr;40(3):531-533. doi: 10.1007/s10875-020-00747-0. Epub 2020 Jan 22.

Abstract

The hyper IgM syndromes are a group of rare primary immunodeficiency disorders. Currently 6 classes of HIGM are described. X-linked HIGM is also called the type 1 HIGM is the commonest variant in which children present in early infancy with features of combined immunodeficiency. Tuberculosis is a very rare presentation as a presenting symptom in HIGM. Here, we describe a child with XHIGM with recurrent tuberculosis.

Keywords: Hyper IgM; Immunodeficiency; Immunoglobulin; Tuberculosis.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Child, Preschool
  • Humans
  • Hyper-IgM Immunodeficiency Syndrome, Type 1 / diagnosis*
  • Image-Guided Biopsy
  • Infant
  • Male
  • Recurrence
  • Respiratory Insufficiency
  • Skin Tests
  • Tomography, X-Ray Computed
  • Tuberculosis, Pulmonary / diagnosis*
  • X-Linked Combined Immunodeficiency Diseases / diagnosis*