Silent T1 mapping using the variable flip angle method with B1 correction

Magn Reson Med. 2020 Aug;84(2):813-824. doi: 10.1002/mrm.28178. Epub 2020 Jan 21.

Abstract

Purpose: To compare the silent rotating ultrafast imaging sequence (RUFIS) to a traditional Cartesian spoiled gradient-echo (SPGR) acquisition scheme for variable flip angle (VFA) T1 mapping.

Methods: A two-point VFA measurement was performed using RUFIS and Cartesian SPGR in a quantitative phantom and healthy volunteers. To correct for B1 errors, a novel silent magnetization prepared B1 map acquisition (SIMBA) was developed, which combined with RUFIS VFA allows for a completely silent T1 mapping protocol.

Results: The silent protocol was found to have comparable repeatability but higher reproducibility in vivo compared to the standard SPGR protocol, and showed no increase in acoustic noise levels above background noise levels compared to a 33 dBA increase for the SPGR acquisition.

Conclusions: VFA T1 mapping using RUFIS is a feasible alternative to SPGR, achieving silent T1 mapping with comparable acquisition time.

Keywords: T1; MRI; ZTE; quantitative; silent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Brain*
  • Healthy Volunteers
  • Humans
  • Magnetic Resonance Imaging*
  • Phantoms, Imaging
  • Reproducibility of Results