Skin-Selective CD8 T-Cell Depletion by Photoimmunotherapy Inhibits Human Cutaneous Acute Graft-Versus-Host Disease

J Invest Dermatol. 2020 Jul;140(7):1455-1459.e6. doi: 10.1016/j.jid.2019.12.009. Epub 2019 Dec 24.

Authors

Lukas Freund¹, Stephanie Oehrl¹, Galina Gräbe¹, Patrick Gholam¹, Thomas Plum², Knut Schäkel³

Affiliations

¹ Department of Dermatology, Heidelberg University Hospital, Heidelberg, Germany.
² Division of Cellular Immunology, German Cancer Research Center, Heidelberg, Germany.
³ Department of Dermatology, Heidelberg University Hospital, Heidelberg, Germany. Electronic address: knut.schaekel@med.uni-heidelberg.de.

PMID: 31881211
DOI: 10.1016/j.jid.2019.12.009

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Acute Disease
Animals
Bone Marrow Transplantation
CD8-Positive T-Lymphocytes / cytology*
Cell Movement
Graft vs Host Disease / prevention & control*
Humans
Immunotherapy*
Leukocytes, Mononuclear / metabolism
Lymphocyte Activation
Lymphocyte Depletion*
Mice
Mice, Inbred NOD
Photochemistry*
Skin / metabolism*
Spleen / metabolism