Executive summary of the Consensus Statement of the Transplant Infection Study Group (GESITRA) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the National Transplant Organization (ONT) on the Selection Criteria of Donors of Solid Organs in relation to Infectious Diseases
Enferm Infecc Microbiol Clin (Engl Ed). 2020 Oct;38(8):379-389.
doi: 10.1016/j.eimc.2019.10.016.
Epub 2019 Dec 24.
[Article in
English,
Spanish]
Authors
Oscar Len
1
, Ibai Los-Arcos
2
, José María Aguado
3
, Marino Blanes
4
, Marta Bodro
5
, Jordi Carratalà
6
, Elisa Cordero
7
, María Carmen Fariñas
8
, Mario Fernández-Ruiz
3
, Jesús Fortún
9
, Joan Gavaldà
2
, Francisco López-Medrano
3
, Rogelio López-Vélez
9
, Carlos Lumbreras
3
, Beatriz Mahillo
10
, María Ángeles Marcos
11
, Pilar Martin-Dávila
9
, José Miguel Montejo
12
, Asunción Moreno
5
, Patricia Muñoz
13
, Francesca Norman
9
, José Luis Pérez-Sáenz
14
, Tomás Pumarola
2
, Núria Sabé
6
, Rafael San-Juan
3
, Elisa Vidal
15
, Beatriz Domínguez-Gil
10
; Transplant Infection Study Group GESITRA of the Spanish Society of Infectious Diseases and Clinical Microbiology SEIMC the National Transplant Organization ONT
Affiliations
- 1 Hospital Universitari Vall d'Hebrón, Barcelona, Spain. Electronic address: oscar.len@vhir.org.
- 2 Hospital Universitari Vall d'Hebrón, Barcelona, Spain.
- 3 Hospital Universitario 12 de Octubre, Madrid, Spain.
- 4 Hospital Universitario y Politécnico La Fe, Valencia, Spain.
- 5 Hospital Clínic-IDIBAPS, Barcelona, Spain.
- 6 Hospital Universitari de Bellvitge-IDIBELL, Barcelona, Spain.
- 7 Hospital Virgen del Rocío, Sevilla, Spain.
- 8 Hospital Universitario Marqués de Valdecilla, Santander, Spain.
- 9 Hospital Universitario Ramón y Cajal, Madrid, Spain.
- 10 Organización Nacional de Trasplantes, Madrid, Spain.
- 11 Hospital Clínic, Barcelona, Spain.
- 12 Hospital Universitario de Cruces, Vizcaya, Spain.
- 13 Hospital General Universitario Gregorio Marañón, Madrid, Spain.
- 14 Hospital Universitario Son Espases, Palma de Mallorca, Spain.
- 15 Hospital Universitario Reina Sofía, Córdoba, Spain.
Abstract
The immunosuppressive treatment that recipients receive from a solid organ transplantation hinders the defensive response to infection. Its transmission from the donor can cause dysfunction or loss of the graft and even death of the recipient if proper preventive measures are not established. This potential risk should be thoroughly evaluated to minimise the risk of infection transmission from donor to recipient, especially with organ transplantation from donors with infections, without increasing graft dysfunction and morbidity and mortality in the recipient. This document aims to review current knowledge about infection screening in potential donors and offer clinical and microbiological recommendations about the use of organs from donors with infection based on available scientific evidence.
Keywords:
Donación; Donation; Infección; Infection; Solid organ transplantation; Transmisión; Transmission; Trasplante de órgano sólido.
Copyright © 2019 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.
Publication types
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Practice Guideline
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Research Support, Non-U.S. Gov't
MeSH terms
-
Communicable Diseases*
-
Consensus
-
Humans
-
Organ Transplantation*
-
Patient Selection*
-
Societies, Medical
-
Spain
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Tissue Donors*