In vitro expansion of human sperm through nuclear transfer

Xiaoyu Merlin Zhang; Keliang Wu; Yuxuan Zheng; Han Zhao; Junpeng Gao; Zhenzhen Hou; Meiling Zhang; Jiaoyang Liao; Jingye Zhang; Yuan Gao; Yuanyuan Li; Lin Li; Fuchou Tang; Zi-Jiang Chen; Jinsong Li

doi:10.1038/s41422-019-0265-1

In vitro expansion of human sperm through nuclear transfer

Cell Res. 2020 Apr;30(4):356-359. doi: 10.1038/s41422-019-0265-1. Epub 2019 Dec 18.

Authors

Xiaoyu Merlin Zhang^#¹, Keliang Wu^#², Yuxuan Zheng^#^{3

4

5}, Han Zhao^#², Junpeng Gao^{3

4}, Zhenzhen Hou², Meiling Zhang⁶, Jiaoyang Liao¹, Jingye Zhang², Yuan Gao², Yuanyuan Li¹, Lin Li³, Fuchou Tang^{7

8

9}, Zi-Jiang Chen¹⁰, Jinsong Li^{11

12}

Affiliations

¹ State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, China.
² Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250001, China.
³ Beijing Advanced Innovation Center for Genomics, College of Life Sciences, Peking University, Beijing, 100871, China.
⁴ Biomedical Institute for Pioneering Investigation via Convergence, Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing, 100871, China.
⁵ Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China.
⁶ Center for Reproductive Medicine, Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
⁷ Beijing Advanced Innovation Center for Genomics, College of Life Sciences, Peking University, Beijing, 100871, China. tangfuchou@pku.edu.cn.
⁸ Biomedical Institute for Pioneering Investigation via Convergence, Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing, 100871, China. tangfuchou@pku.edu.cn.
⁹ Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China. tangfuchou@pku.edu.cn.
¹⁰ Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250001, China. chenzijiang@hotmail.com.
¹¹ State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, China. jsli@sibcb.ac.cn.
¹² School of Life Science and Technology, Shanghai Tech University, 100 Haike Road, Shanghai, 201210,, China. jsli@sibcb.ac.cn.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Nucleus / metabolism*
Haploidy*
Humans
Male
Nuclear Transfer Techniques*
Spermatozoa / cytology*