Contemporary management techniques of asthma in obese patients

Expert Rev Respir Med. 2020 Mar;14(3):249-257. doi: 10.1080/17476348.2020.1706486. Epub 2019 Dec 25.

Abstract

Introduction: Obesity-associated asthma represents a heterogeneous group of clinical phenotypes, including an adult-onset phenotype. These patients often have difficult to control symptoms and often are less likely to respond to conventional asthma therapies.Areas covered: This review covers the effects of lifestyle interventions, including diet and weight loss, effect asthma outcomes and how obesity-associated asthma responds to conventional approaches to asthma management.Expert opinion: Management of obesity-associated asthma should include lifestyle modifications aimed at weight reduction, management of other co-morbidities, and limiting systemic steroids. As many of these patients have non-Th2 asthma, long-acting muscarinic antagonists and macrolides may be potentially helpful. Medications to treat metabolic syndrome.

Keywords: Asthma; diet; obesity; oxidative stress; treatment.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Asthma / diet therapy
  • Asthma / etiology
  • Asthma / therapy*
  • Diet
  • Disease Management
  • Humans
  • Life Style
  • Muscarinic Antagonists / therapeutic use
  • Obesity / complications
  • Obesity / diet therapy
  • Obesity / therapy*
  • Weight Loss

Substances

  • Muscarinic Antagonists