Assessing Discrepancies in Neurocognitive and Patient-Reported Measures of Brain Tumor Survivors

Oncol Nurs Forum. 2020 Jan 1;47(1):E1-E12. doi: 10.1188/20.ONF.E1-E12.

Abstract

Objectives: To examine the association between performance-based neurocognitive and patient-reported cognitive function tests and identify characteristics that may explain observed discrepancies as a means to advance intervention development.

Sample & setting: 40 adults diagnosed with a primary brain tumor (PBT) (high-grade, n = 35) were recruited from two academic neuro-oncology clinics in North Carolina.

Methods & variables: Eligibility included a Mini-Mental State Examination score of 24 or greater, having completed cancer treatment, and having tumor stability. Participants completed performance-based neurocognitive and patient-reported cognitive function, demographic, and symptom assessment tests at one time point.

Results: Neurocognitive impairments included executive control, memory, and attention. Age, time since diagnosis, and tumor- or treatment-specific variables were not associated with neurocognitive or patient-reported cognitive function. Those reporting worse cognitive impairment tended also to report greater severity of PBT-specific and depressive symptoms.

Implications for nursing: Patient-reported cognitive concerns warrant additional assessment for potential interventions to maintain function.

Keywords: adult patients with cancer; neurocognitive performance; primary brain tumor; survivors.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Brain Neoplasms / physiopathology*
  • Cancer Survivors / statistics & numerical data*
  • Cognition / physiology*
  • Cognitive Dysfunction / physiopathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • North Carolina
  • Patient Reported Outcome Measures
  • Symptom Assessment / statistics & numerical data*