Drug-Induced Autoimmune Hepatitis From Hydralazine Leading to Acute Liver Failure and Liver Transplantation

Jasleen Grewal; Angela Doan; Annie S Hong; Arpit Amin; Jason V Scapa; Ramy Hanna; Francisco Durazo; Beshoy Yanny

doi:10.14309/crj.0000000000000252

Drug-Induced Autoimmune Hepatitis From Hydralazine Leading to Acute Liver Failure and Liver Transplantation

ACG Case Rep J. 2019 Oct 23;6(10):e00252. doi: 10.14309/crj.0000000000000252. eCollection 2019 Oct.

Authors

Jasleen Grewal¹, Angela Doan¹, Annie S Hong², Arpit Amin³, Jason V Scapa⁴, Ramy Hanna¹, Francisco Durazo^{1

3}, Beshoy Yanny¹

Affiliations

¹ Department of Medicine, University of California at Los Angeles, Los Angeles, CA.
² Department of Medicine, University of Nevada Las Vegas, Las Vegas, NV.
³ Department of Surgery, University of California at Los Angeles, Los Angeles, CA.
⁴ Department of Pathology, University of California at Los Angeles, Los Angeles, CA.

Abstract

We describe a woman with no previous liver disease who developed drug-induced autoimmune hepatitis from hydralazine prescribed to her for hypertension. Despite the discontinuation of the medication, she developed acute liver failure and subsequently underwent successful liver transplantation. She survived and had a good clinical outcome.

Publication types

Case Reports