Using the impedance plethysmographic method of rheography it is possible to ascertain the tone of the peripheral resistance vessels directly by simple means. Previous studies have shown that there is a close relationship between peripheral vasodilatation at rest and normal course of pregnancy. In the present study, rheographic changes were studied in patients with normal pregnancy (n = 27, Group 1), diabetes mellitus (n = 18, Group 2), "pregnancy-induced hypertension" (n = 10, Group 3), and chronic placental insufficiency (n = 16, Group 4) during and following a low-temperature stimulus. After exposure to icy water, the Group 1 subjects showed a 40% reduction in rheographic amplitude, Groups 2 and 3 a 25% reduction, while Group 4 patients showed no signs of vasoconstriction going beyond the resting state (p less than 0.001). The four groups also differed considerably as regards vessel wall behavior in the recovery phase. The study confirms that the amplitude of the peripheral rheogram is a good indicator for detecting high-risk pregnancies. The amplitude pattern under thermal stimulation also provides further information on the dynamic behavior of the resistance vessels in normal and pathologic pregnancies.