Primary cutaneous alveolar rhabdomyosarcoma in an adolescent - A challenging diagnosis

Pediatr Dermatol. 2020 Jan;37(1):184-186. doi: 10.1111/pde.14055. Epub 2019 Dec 4.

Abstract

Primary cutaneous alveolar rhabdomyosarcoma is an extremely rare and highly aggressive soft tissue sarcoma that predominantly arises on the extremities and perineum of adolescents and young adults. Dermatologists should be aware of these tumors in order to promptly make the diagnosis and initiate treatment.

Keywords: PAX3-FOXO1; PAX7-FOXO1; Rhabdomyosarcoma.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Dactinomycin / therapeutic use
  • Humans
  • Ifosfamide / therapeutic use
  • Male
  • Positron-Emission Tomography
  • Rhabdomyosarcoma, Alveolar / diagnosis*
  • Rhabdomyosarcoma, Alveolar / diagnostic imaging
  • Rhabdomyosarcoma, Alveolar / drug therapy
  • Rhabdomyosarcoma, Alveolar / pathology
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / diagnostic imaging
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / pathology
  • Vincristine / therapeutic use

Substances

  • Dactinomycin
  • Vincristine
  • Ifosfamide

Supplementary concepts

  • IVA protocol